存在主义哲学
一、选择原因及应用消化道传染病
口腔鳞癌组织中肿瘤转移相关基因1（MTA1）在蛋白和mRNA的表达水平，揭示其与口腔鳞癌（OSCC）发生、发展的关系。方法采用免疫组织化学法和原位杂交技术检测46例OSCC标本、15例口腔黏膜白斑与20例正常口腔黏膜标本中MTAl基因的表达水平，并分析其与OSCC临床病理学参数的关系。结果MTA1蛋白和MTA1mRNA在OSCC组织中的表达水平显著高于口腔黏膜白斑和正常口腔黏膜（P〈0．05），口腔黏膜白斑中MTA1蛋白和MTA1mRNA表达水平显著高于口腔正常黏膜（P〈0．01），MTA1蛋白和MTA1mRNA表达与肿瘤浸润深度和淋巴结转移密切相关（P〈0．05）。结论MTA1基因在蛋白和mRNA的表达水平在OSCC发生、发展及浸润转移过程中起一定促进作用，有望成为判断OSCC预后及选择方案的一个新肿瘤标志物。 2、2伞下一肩雨查阅NCBI得到MTA1相关信息并获得目的基因
PREDICTED: Gorilla gorilla gorilla metastasis associated 1 (MTA1), mRNA
NCBI Reference Sequence: XM_004055801.1
FASTA Graphics
∙ Comment
∙ Features
∙ Sequence
LOCUS XM_004055801 2872 bp mRNA linear PRI 03-DEC-2012
DEFINITION PREDICTED: Gorilla gorilla gorilla metastasis associated 1 (MTA1),
mRNA.
ACCESSION XM_004055801
VERSION XM_004055801.1 GI:426378238
KEYWORDS .
SOURCE Gorilla gorilla gorilla (western lowland gorilla)
ORGANISM Gorilla gorilla gorilla
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Gorilla.
COMMENT MODEL REFSEQ: This record is predicted by automated computational
analysis. This record is derived from a genomic sequence
(NW_004005914) annotated using gene prediction method: GNOMON,
supported by mRNA and EST evidence.
Also see:
Documentation of NCBI's Annotation Process
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Status :: Full annotation
Annotation Version :: Gorilla gorilla Annotation Release 100
Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline
Annotation Method :: Best-placed RefSeq; Gnomon
Features Annotated :: Gene; mRNA; CDS; ncRNA
##Genome-Annotation-Data-END##
绝对大牌
FEATURES Location/Qualifiers
source 1..2872
/organism="Gorilla gorilla gorilla"
/mol_type="mRNA"
/sub_species="gorilla"
/db_xref="taxon:9595"
/chromosome="14"
gene 1..2872
/gene="MTA1"
/note="Derived by automated computational analysis using
gene prediction method: GNOMON. Supporting evidence
includes similarity to: 4 mRNAs, 303 ESTs, 7 Proteins"
/db_xref="GeneID:101134898"
misc_feature 104..106
/gene="MTA1"
/note="upstream in-frame stop codon"
CDS 212..2359
/gene="MTA1"
/codon_start=1
/product="metastasis-associated protein MTA1"
/protein_id="XP_004055849.1"
/db_xref="GI:426378239"
/db_xref="GeneID:101134898"
/translation="MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVC
FYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQ
LRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTL
网上冲印系统 LADKGEIRVGNRYQADITDLLKEGEEDGRDQSKLETKVWEAHNPLTDKQIDQFLVVAR
SVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQG
GPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTD
RYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRA
CESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSP
中国麻风皮肤病杂志
HGLPARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAI
KAECTARLPEASQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPA
KVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLLMPSRGLANHGQTRHMGPSRNLLLN
GKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAAR
RPYKPIALRQSQALPLRPPPPAPVNDEPIVIED"
ORIGIN
1 tcctcctctt cctctcccgc ccgcgccgcg gccctcccgt ccctgcgcgg cctcggcggc
